Breadcrumb
Large Scale Discovery Approaches to Understanding Circadian Networks in Health and Disease
Wed 01 May 2013, 16:00
Steve Kay
University of Southern California
Organiser: Jon Keating, FRS
ABSTRACT
This talk will look at recent results that explore how clocks regulate processes such as glucose homeostasis and feeding in mammals. We will also present data on the identification of the first proof of concept chemical probes for the manipulation of circadian clocks by small molecules. Target deconvolution of these chemical probes is revealing novel features of clock function. Computational approaches to mine existing data collections for comprehensive network reconstruction will also be described, and how such approaches present circadian clocks as highly interesting targets for development of novel therapeutics in multiple disease areas.
Venue: Lecture Theatre 2, School of Chemistry