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Bayesian alignment using hierarchical models, with applications in protein bioinformatics

by Peter J. Green, School of Mathematics, University of Bristol, Bristol BS8 1TW, UK. and
Kanti V. Mardia, Department of Statistics, School of Mathematics, University of Leeds, Leeds, LS2 9JT, UK.

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The paper: PostScript; PDF.

Data for examples in sections 4.1 and 4.2

  • Gel data in various formats: plain text file; R source format; R image format; R print output
  • Protein active sites
    • Data in various formats: plain text file; R source format; R image format; R print output
    • Origin of data: the two examples are taken from the pdb data bank (a data bank of protein structures about 33,000 proteins available on the website http://www.rcsb.org/pdb/) and their pdb codes are 1cyd (the x configuration, 40 points) and 1a27 (the y configuration, 63 points). These two proteins belongs to the same family in what is called a SCOP classification (the family is Tyrosine-dependent oxireductase).
    • Plot of MCMC diagnostics for a typical run as described in Section 4.2


Professor Peter Green, School of Mathematics, University of Bristol, Bristol, BS8 1TW, UK.
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